In Episode 6, we discussed treatment of Disseminated Intravascular Coagulation (DIC) which included the administration of tranexamic acid (TXA). Did you know TXA is still effective in non-inflammatory DIC caused by metastatic prostate carcinoma and/or acute promyelocytic leukemia? These cancers can result in hyperfibrinolysis syndrome which results in significant bleeding; similar to what occurs in traumatic injuries.
Boral, B. M., Williams, D. J., & Boral, L. I. (2017). Disseminated intravascular coagulation. American Journal of Clinical Pathology, 146(6), 670-680.
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