Did You Know? (Ep. 6)

In Episode 6, we discussed treatment of Disseminated Intravascular Coagulation (DIC) which included the administration of tranexamic acid (TXA).  Did you know TXA is still effective in non-inflammatory DIC caused by metastatic prostate carcinoma and/or acute promyelocytic leukemia?  These cancers can result in hyperfibrinolysis syndrome which results in significant bleeding; similar to what occurs in... Continue Reading →

Did You Know? (Ep. 5)

In Episode 5, we discussed the detrimental effects of hyponatremia over-correction which included osmotic demyelination syndrome (ODS).  Did you know ODS used to be called central pontine myelinolysis (CPM) or central pontine demyelination?  These narrow terms were updated after realizing nerve cells outside of the brain stem's pons were also affected by rapid increases in... Continue Reading →

Did You Know? (Ep. 3)

In Episode 3, we discussed sodium chloride's role in the treatment of hypochloremia.  Did you know hypochloremia is often accompanied by hypokalemia?  Serum potassium decreases as potassium ions enter the cell to replace the lost hydrogen ions.  If a patient develops metabolic alkalosis while in a volume-overloaded state (e.g. Cirrhosis, CHF), replenishing chloride with potassium... Continue Reading →

Did You Know? (Ep. 2)

In Episode 2, we discussed hepatopathy complications associated with the Sickle Cell Disease (SCD) patient receiving multiple blood transfusions.  Did you know individuals receiving repetitive transfusions may also experience hepatic iron overload, subsequently requiring chelation therapy? Chelation therapy involves the injection of a chelating agent such as EDTA (ethylene diamine tetra-acetic acid), a synthetic amino... Continue Reading →

Did You Know? (Ep. 1)

In Episode 1, we discussed Atropine's ineffectiveness in relation to Traumatic Brain Injury (TBI) and Herniation Syndrome.  Did you know Atropine administration is sometimes used as a test for brain stem damage and ultimately death? Typically, a 3mg injection is utilized to evaluate the patient's response.  If the patient has an increase in heart rate... Continue Reading →

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