Seizures demand fast decisions, but the best answers aren’t always simple. In this episode, we sit down with Skyee Edwards, a pharmacist, to break down seizure cessation and prophylaxis in real-world emergencies.

We go beyond traditional benzodiazepine-first thinking and explore how current evidence guides escalation to agents like levetiracetam, valproate, and fosphenytoin. Then we step into the evolving edge of care: where ketamine and lacosamide fits in refractory status epilepticus, and when propofol becomes a tool instead of a last resort. We also dig into common pitfalls such as delayed escalation, under-dosing, and not appreciating non-convulsive status.

If you manage seizures in any high-acuity environment, this conversation will sharpen your approach from first contact through definitive control.

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Guest

Skyee Edwards, PharmD, BCCCP graduated from Wilkes University Nesbitt School of Pharmacy in 2021. Upon graduating, she completed a PGY1 Acute Care Pharmacy Residency at WVU Medicine followed by a PGY2 in Critical Care at WVU Medicine. She resides on staff as the Emergency Medicine Pharmacy Specialist.

Contact: skyee.edwards@wvumedicine.org

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